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\u201c\u9019\u9805\u7642\u6cd5\u7684\u6539\u9032\u662f\u6709\u5de8\u5927\u9700\u6c42\u7684\uff0c\u201d\u4ed6\u88dc\u5145\u9053\uff0c\u201c\u5728\u60a3\u8005\u8eab\u4e0a\u9032\u884c\u8a66\u9a57\u4e26\u4e0d\u904e\u5206\u3002\u201d \u4e0d\u904e\uff0c\u8cd3\u5915\u6cd5\u5c3c\u4e9e\u5927\u5b78(Pennsylvania)\u7684\u76ae\u819a\u75c5\u5c08\u5bb6\u55ac\u6cbb\u00b7\u67ef\u85a9\u840a\u5229\u65af(George Cotsarelis)\u535a\u58eb\uff0c\u6975\u529b\u4e3b\u5f35\u5728\u9032\u884c\u66f4\u6df1\u5165\u7684\u7814\u7a76\u4e4b\u524d\u4fdd\u6301\u8b39\u614e\u3002\u4ed6\u8868\u793a\uff0c\u6291\u5236\u514d\u75ab\u7cfb\u7d71\u6d3b\u52d5\u7684\u85e5\u7269\u5c0d\u56e0\u514d\u75ab\u53cd\u61c9\u904e\u5ea6\u9748\u654f\u800c\u5f15\u767c\u7684\u75be\u75c5\u6709\u6548\uff0c\u9019\u4e0d\u51fa\u5947\u3002 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\u67ef\u85a9\u840a\u5229\u65af\u535a\u58eb\u8aaa\uff0c\u5047\u5982\u53ef\u4ee5\u5c40\u90e8\u61c9\u7528\u9b6f\u7d22\u5229\u66ff\u5c3c\uff0c\u201c\u90a3\u5c07\u662f\u9a5a\u4eba\u7684\u7a81\u7834\u201d\u3002\u5728\u6b64\u4e4b\u524d\uff0c\u201c\u8981\u6c42\u7528\u8a72\u7642\u6cd5\u6cbb\u7642\u7684\u60a3\u8005\u672a\u514d\u986f\u5f97\u8349\u7387\uff0c\u6211\u662f\u4e0d\u6703\u7d66\u4ed6\u5011\u958b\u8655\u65b9\u7684\u201d\u3002 \u5fc5\u6cbb\u59a5\u65bd\u8cb4\u5bf6\u516c\u53f8(Bristol-Myers Squibb)\u7684\u62c9\u6590\u723e\u00b7\u514b\u840a\u56e0(Raphael Clyne)\u535a\u58eb\u5728\u54e5\u502b\u6bd4\u4e9e\u5927\u5b78\u7576\u6559\u6388\u671f\u9593\u662f\u9019\u9805\u7814\u7a76\u7684\u8ca0\u8cac\u4eba\u4e4b\u4e00\uff0c\u4ed6\u8868\u793a\uff0c\u7814\u7a76\u5718\u968a\u62ff\u8001\u9f20\u505a\u6e2c\u8a66\u6642\u7528\u904e\u818f\u5291\u548c\u7247\u5291\uff0c\u4e26\u4e14\u6253\u7b97\u9032\u884c\u818f\u5291\u7684\u4eba\u9ad4\u6e2c\u8a66\u3002 \u4ed6\u8a8d\u70ba\u9b6f\u7d22\u5229\u66ff\u5c3c\u8fc4\u4eca\u70ba\u6b62\u9084\u662f\u201c\u4e00\u7a2e\u50f9\u683c\u9ad8\u6602\u7684\u6cbb\u7642\u624b\u6bb5\u3002\u5c31\u6211\u5011\u6cbb\u7642\u7684\u70ba\u6578\u4e0d\u591a\u7684\u60a3\u8005\u800c\u8a00\uff0c\u5b83\u6216\u8a31\u662f\u6709\u6548\u7684\uff0c\u5728\u5b89\u5168\u6027\u65b9\u9762\u7684\u8868\u73fe\u4f3c\u4e4e\u4e5f\u8aaa\u5f97\u904e\u53bb\u3002\u4f46\u9664\u975e\u9032\u884c\u66f4\u5927\u898f\u6a21\u7684\u6e2c\u8a66\uff0c\u5426\u5247\u6211\u7d55\u4e0d\u6703\u5b8c\u5168\u8a8d\u53ef\u9019\u7a2e\u7642\u6cd5\u201d\u3002 \u7814\u7a76\u5718\u968a\u9084\u6253\u7b97\u5c0d\u53e6\u5916\u4e00\u7a2eJAK\u6291\u88fd\u5291\u2014\u2014\u8a17\u6cd5\u66ff\u5c3c(Tofacitinib)\u2014\u2014\u9032\u884c\u4eba\u9ad4\u6e2c\u8a66\u3002\u9019\u662f\u4e00\u7a2e\u7372\u6279\u6cbb\u7642\u985e\u98a8\u6fd5\u95dc\u7bc0\u708e\u7684\u85e5\u7269\uff0c\u80fd\u8b93\u8001\u9f20\u9577\u51fa\u6bdb\u9aee\u3002\u4eca\u5e746\u6708\uff0c\u8036\u9b6f\u5927\u5b78(Yale)\u76ae\u819a\u75c5\u5c08\u5bb6\u5e03\u840a\u7279\u00b7\u91d1(Brett King)\u535a\u58eb\u5ba3\u7a31\uff0c\u8a17\u6cd5\u66ff\u5c3c(Tofacitinib)\u80fd\u4fc3\u9032\u7537\u6027\u666e\u79bf\u60a3\u8005\u7684\u6bdb\u9aee\u751f\u9577\uff0c\u4e14\u6c92\u6709\u4efb\u4f55\u526f\u4f5c\u7528\u3002\u666e\u79bf\u662f\u4e00\u7a2e\u5e7e\u4e4e\u53ef\u4ee5\u9020\u6210\u5168\u8eab\u6bdb\u9aee\u5168\u90e8\u812b\u843d\u7684\u75be\u75c5\u3002 \u5c0d\u5e03\u840a\u6069\u800c\u8a00\uff0c\u670d\u7528\u9b6f\u7d22\u5229\u66ff\u5c3c\u4e94\u500b\u6708\u63db\u4f86\u4e86\u6eff\u982d\u7684\u9aee\u7d72\u3002\u4ed6\u539f\u5148\u7684\u982d\u9aee\u662f\u9ed1\u8272\u7684\uff0c\u4e0d\u77e5\u9053\u70ba\u4ec0\u9ebc\uff0c\u65b0\u9577\u51fa\u4f86\u7684\u982d\u9aee\u537b\u662f\u767d\u8272\u7684\u3002 \u4f46\u4ed6\u8aaa\uff0c\u201c\u76f8\u6bd4\u9762\u5c0d\u4eba\u5011\u7121\u8072\u7684\u6210\u898b\uff0c\u9019\u6a23\u8981\u597d\u53d7\u591a\u4e86\u201d\u2014\u2014\u4ed6\u4ee5\u524d\u7e3d\u611f\u89ba\u4eba\u5011\u5728\u6253\u91cf\u4ed6\u7684\u79bf\u6591\u3002\u4ed6\u9084\u8868\u793a\uff0c\u5305\u62ec\u8f15\u5fae\u8ca7\u8840\u5728\u5167\u7684\u526f\u4f5c\u7528\u662f\u975e\u5e38\u5c0f\u7684\u3002 \u4f86\u6e90\uff1a\u4e2d\u65b0\u793e","rel":"","context":"In 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2017","format":false,"excerpt":"\u6211\u5abd\u5abd\u66fe\u7d93\u62ff\u6211\u300c\u98f2\u7528\u554f\u984c\u300d\u958b\u73a9\u7b11\u3002\u4f46\u4f60\u5728\u8a8d\u70ba\u6211\u6709\u559d\u9152\u554f\u984c\u4e4b\u524d\uff0c\u6211\u5f97\u8b93\u4f60\u77e5\u9053\u6211\u7684\u554f\u984c\u548c\u9152\u7121\u95dc\u3002\u5176\u5be6\u5c31\u662f\u6211\u5e7e\u4e4e\u6bcf\u5929\u90fd\u8981\u559d\u5169\u5347\u88dd\u7121\u7cd6\u6c7d\u6c34\uff0c\u6211\u5abd\u89ba\u5f97\u5b83\u662f\u4e00\u500b\u554f\u984c\u3002\u5728\u6211\u958b\u59cb\u95dc\u6ce8\u6211\u6b63\u5728\u5c07\u4ec0\u9ebc\u9001\u9032\u6211\u7684\u8eab\u9ad4\u5f8c\uff0c\u5e7e\u5e74\u524d\uff0c\u6211\u64fa\u812b\u4e86\u6211\u7684\u7121\u7cd6\u6c7d\u6c34\u4e0a\u766e\u75c7\u3002\u6211\u505c\u6b62\u8cfc\u8cb7\u4efb\u4f55\u542b\u6709\u4eba\u5de5\u751c\u5473\u5291\u7684\u6771\u897f\u3002\u96d6\u7136\u6211\u7576\u6642\u4e26\u4e0d\u77e5\u9053\u4eba\u9020\u751c\u5473\u5291\u5728\u6e1b\u80a5\u4e0a\u6c92\u6709\u4ec0\u9ebc\u7279\u5225\u6548\u679c\uff0c\u4e5f\u4e0d\u77e5\u9053\u5b83\u6703\u589e\u52a0\u4e00\u500b\u4eba\u60a3\u7cd6\u5c3f\u75c5\u7684\u5e7e\u7387\uff0c\u4f46\u6211\u77e5\u9053\u7684\u662f\u6211\u4e0d\u60f3\u6211\u7684\u5bb6\u5ead\u98f2\u98df\u88cf\u6709\u592a\u591a\u7684\u4eba\u5de5\u98df\u54c1\u3002\u6211\u6700\u521d\u53ea\u662f\u8ddf\u8457\u76f4\u89ba\u505a\u51fa\u4e86\u90a3\u500b\u6c7a\u5b9a\uff0c\u4f46\u73fe\u5728\u6211\u7684\u8178\u9053\u6709\u7406\u7531\u611f\u8b1d\u6211\u3002 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