{"id":120777,"date":"2016-06-07T12:04:19","date_gmt":"2016-06-07T19:04:19","guid":{"rendered":"http:\/\/old.newsforchinese.com\/v3\/?p=120777"},"modified":"2016-06-07T12:04:19","modified_gmt":"2016-06-07T19:04:19","slug":"tecentriq%ef%bc%9a%e6%99%9a%e6%9c%9f%e8%86%80%e8%83%b1%e7%99%8c%e6%96%b0%e8%97%a5","status":"publish","type":"post","link":"https:\/\/newsforchinese.com\/v3\/2016\/06\/07\/tecentriq%ef%bc%9a%e6%99%9a%e6%9c%9f%e8%86%80%e8%83%b1%e7%99%8c%e6%96%b0%e8%97%a5\/","title":{"rendered":"Tecentriq\uff1a\u665a\u671f\u8180\u80f1\u764c\u65b0\u85e5"},"content":{"rendered":"<p>\u4e00\u7a2e\u65b0\u6279\u51c6\u7684\u85e5\u6709\u52a9\u65bc\u963b\u6b62\u665a\u671f\u8180\u80f1\u764c\u60a3\u8005\u816b\u7624\u64f4\u6563\u3002<!--more--><\/p>\n<p>\u9019\u7a2e\u85e5\u6b63\u5f0f\u540d\u7a31\u70baatezolizumab\uff0c\u92b7\u552e\u540d\u7a31\u70baTecentriq\uff0c\u4f5c\u7528\u6a5f\u7406\u8207\u5e6b\u52a9\u963b\u6b62\u524d\u7e3d\u7d71Jimmy Carter\u665a\u671f\u9ed1\u7d20\u7624\u64f4\u6563\u7684Keytruda\u4e00\u6a23\u3002\u9019\u7a2e\u65b0\u85e5\u7269\u76f4\u63a5\u4f5c\u7528\u65bc\u90a3\u4e9b\u6467\u6bc0\u816b\u7624\u7684\u514d\u75ab\u7d30\u80de\u3002<\/p>\n<p>NYU Langone Medical Center\u7814\u7a76\u5718\u968a\u7a31\uff0c\u5728\u4f7f\u7528\u9019\u7a2e\u85e5\u7269\u7684\u7814\u7a76\u4eba\u7fa4\u4e2d\uff0c24%\u7684\u4eba\u816b\u7624\u64f4\u6563\u88ab\u963b\u6b62\uff0c\u816b\u7624\u7e2e\u5c0f\u4e8630%\u3002<\/p>\n<p>\u65e9\u4e9b\u6642\u5019\u7684\u65b9\u6cd5\u5305\u62ec\u767c\u52d5\u514d\u75ab\u7cfb\u7d71\uff0c\u4f46\u662f\u9019\u4e9b\u65b9\u6cd5\u4e26\u4e0d\u7e3d\u662f\u594f\u6548\u3002\u5176\u4ed6\u65b9\u6cd5\uff0c\u5982\u653e\u5927\u75c5\u4eba\u81ea\u8eab\u816b\u7624\u7279\u7570\u6027\u7d30\u80de\uff0c\u4e00\u662f\u8cbb\u5de5\u8cbb\u529b\uff0c\u4e8c\u662f\u4e26\u975e\u5c0d\u6bcf\u500b\u4eba\u90fd\u6709\u6548\u3002<\/p>\n<p>Tecentriq\u4e0a\u500b\u6708\u5df2\u7372\u5f97FDA\u6279\u51c6\uff0c\u4f46\u5b83\u50f9\u683c\u53ef\u662f\u4ee4\u4eba\u548b\u820c\u7684\uff1a\u4e00\u500b\u6708\u7684\u85e5\u8981\u82b1\u8cbb12,500\u5143\u3002<\/p>\n<div class=\"gsp_post_data\" \r\n\t            data-post_type=\"post\" \r\n\t            data-cat=\"health\" \r\n\t            data-modified=\"120\"\r\n\t            data-created=\"1465301059\"\r\n\t            data-title=\"Tecentriq\uff1a\u665a\u671f\u8180\u80f1\u764c\u65b0\u85e5\" \r\n\t            data-home=\"https:\/\/newsforchinese.com\/v3\"><\/div>","protected":false},"excerpt":{"rendered":"<p>\u4e00\u7a2e\u65b0\u6279\u51c6\u7684\u85e5\u6709\u52a9\u65bc\u963b\u6b62\u665a\u671f\u8180\u80f1\u764c\u60a3\u8005\u816b\u7624\u64f4\u6563\u3002<\/p>\n","protected":false},"author":1001012,"featured_media":120778,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"categories":[6],"tags":[],"series":[],"class_list":["post-120777","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"aioseo_notices":[],"featured_image_urls":{"thumbnail":"https:\/\/newsforchinese.com\/v3\/wp-content\/uploads\/2016\/06\/Tecentriq-150x150.jpg","medium":"https:\/\/newsforchinese.com\/v3\/wp-content\/uploads\/2016\/06\/Tecentriq-300x200.jpg","large":"https:\/\/newsforchinese.com\/v3\/wp-content\/uploads\/2016\/06\/Tecentriq-600x400.jpg","single_img":"https:\/\/newsforchinese.com\/v3\/wp-content\/uploads\/2016\/06\/Tecentriq-150x150.jpg"},"appp_media":null,"episode_featured_image":"https:\/\/newsforchinese.com\/v3\/wp-content\/uploads\/2016\/06\/Tecentriq.jpg","episode_player_image":"https:\/\/newsforchinese.com\/v3\/wp-content\/uploads\/2022\/11\/avatars-DFF30y5My1u3eZvX-2nXMSw-original.jpg","download_link":"","player_link":"","audio_player":false,"episode_data":{"playerMode":"dark","subscribeUrls":[],"rssFeedUrl":"https:\/\/newsforchinese.com\/v3\/feed\/podcast\/%e8%80%81%e4%b8%ad%e5%bb%a3%e6%92%ad%e9%9b%bb%e5%8f%b0","embedCode":"<blockquote class=\"wp-embedded-content\" data-secret=\"LdIBPRpV0w\"><a href=\"https:\/\/newsforchinese.com\/v3\/2016\/06\/07\/tecentriq%ef%bc%9a%e6%99%9a%e6%9c%9f%e8%86%80%e8%83%b1%e7%99%8c%e6%96%b0%e8%97%a5\/\">Tecentriq\uff1a\u665a\u671f\u8180\u80f1\u764c\u65b0\u85e5<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/newsforchinese.com\/v3\/2016\/06\/07\/tecentriq%ef%bc%9a%e6%99%9a%e6%9c%9f%e8%86%80%e8%83%b1%e7%99%8c%e6%96%b0%e8%97%a5\/embed\/#?secret=LdIBPRpV0w\" width=\"500\" height=\"350\" title=\"&#8220;Tecentriq\uff1a\u665a\u671f\u8180\u80f1\u764c\u65b0\u85e5&#8221; &#8212; News for Chinese \uff0d \u820a\u91d1\u5c71\u7063\u5340No.1\u514d\u8cbb\u83ef\u4eba\u793e\u5340\u5831\u7d19\" data-secret=\"LdIBPRpV0w\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script type=\"text\/javascript\">\n\/* <![CDATA[ *\/\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/newsforchinese.com\/v3\/wp-includes\/js\/wp-embed.min.js\n\/* ]]> *\/\n<\/script>\n"},"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/newsforchinese.com\/v3\/wp-content\/uploads\/2016\/06\/Tecentriq.jpg","jetpack-related-posts":[{"id":139268,"url":"https:\/\/newsforchinese.com\/v3\/2017\/06\/06\/%e7%99%8c%e7%97%87%e6%82%a3%e8%80%85%e7%9a%84%e7%a6%8f%e9%9f%b3%ef%bc%9a%e6%8a%97%e7%99%8c%e8%97%a5%e7%89%a9%e9%80%b2%e6%ad%a5%e9%a1%af%e8%91%97\/","url_meta":{"origin":120777,"position":0},"title":"\u764c\u75c7\u60a3\u8005\u7684\u798f\u97f3\uff1a\u6297\u764c\u85e5\u7269\u9032\u6b65\u986f\u8457\u00a0","author":"Raymond","date":"June 6, 2017","format":false,"excerpt":"\u85e5\u7269\u5728\u5c0d\u6297\u5e38\u898b\u764c\u75c7\u65b9\u9762\u53d6\u5f97\u5de8\u5927\u52dd\u5229\uff0c\u70ba\u5982\u4f55\u6cbb\u7642\u524d\u5217\u817a\u764c\u3001\u4e73\u817a\u764c\u548c\u80ba\u764c\u8a2d\u5b9a\u4e86\u65b0\u7684\u6a19\u6e96\u3002\u751a\u81f3\u6709\u4e00\u7a2e\u300c\u55ae\u4e00\u85e5\u7269\u300d\u53ef\u4ee5\u5c0d\u6297\u591a\u7a2e\u5f62\u5f0f\u7684\u764c\u75c7\u3002\u4ee4\u4eba\u6975\u5176\u5370\u8c61\u6df1\u523b\u7684\u662f\uff1a\u5728\u67d0\u4e9b\u75c5\u4f8b\u4e2d\uff0c\u9019\u4e9b\u85e5\u7269\u7684\u6548\u7528\u53ef\u4ee5\u6301\u7e8c\u8d85\u904e\u4e00\u5e74\uff0c\u9060\u9060\u9577\u65bc\u8a31\u591a\u65b0\u85e5\u7684\u5e7e\u500b\u6708\u3002 \u4ee5\u4e0b\u662f\u4f86\u81ea\u4e16\u754c\u6700\u5927\u764c\u75c7\u6703\u8b70-\u5728\u829d\u52a0\u54e5\u53ec\u958b\u7684American Society Clinical Oncology(\u5168\u7f8e\u81e8\u5e8a\u816b\u7624\u5b78\u6703\uff09\u5927\u6703-\u7684\u4eae\u9ede\u3002 \u524d\u5217\u817a\u764c \u5728\u4e00\u9805\u5c0d1200\u540d\u665a\u671f\u524d\u5217\u817a\u764c\u60a3\u8005\u7684\u7814\u7a76\u4e2d\uff0c\u5728\u88ab\u6dfb\u52a0\u5230\u6a19\u6e96\u91ab\u7642\u5f8c\uff0cJanssen Biotech\u7684Zytiga\u63d0\u9ad8\u4e86\u751f\u5b58\u7387\uff0c\u5ef6\u9072\u4e86\u764c\u75c7\u751f\u9577\u5341\u516b\u500b\u6708\u3002\u9019\u7a2e\u85e5\u7269\u88ab\u6279\u51c6\u7528\u65bc\u6cbb\u7642\u5c0d\u6fc0\u7d20\u6cbb\u7642\u6709\u8010\u85e5\u6027\u7684\u816b\u7624\uff1b\u9019\u9805\u7814\u7a76\u5c07\u5b83\u4f5c\u70ba\u521d\u59cb\u6cbb\u7642\u85e5\u7269\u9032\u884c\u6e2c\u8a66\u3002 \u9019\u9805\u7814\u7a76\u88ab\u63d0\u524d\u7d42\u6b62\uff0c\u56e0\u70ba\u4f7f\u7528Zytiga\u7684\u7537\u6027\u58fd\u547d\u5f97\u5230\u5ef6\u9577\u2014\u2014\u4e09\u5e74\u5f8c\u670966%\u6d3b\u4e86\u4e0b\u4f86\uff0c\u800c\u6c92\u6709\u4f7f\u7528\u9019\u7a2e\u85e5\u7269\u7684\u5c0d\u6bd4\u7d44\u4e09\u5e74\u5f8c\u5b58\u6d3b\u7387\u53ea\u670949%\u3002Zytiga\u9084\u63a8\u9072\u4e86\u764c\u75c7\u60e1\u5316\u6642\u9593\u2014\u201433\u500b\u6708\uff0c\u5c0d\u7167\u7d44\u70ba15\u500b\u6708\u3002 \u5728\u5c0d1900\u540d\u65b0\u8a3a\u665a\u671f\u524d\u5217\u817a\u764c\u7537\u6027\u9032\u884c\u7684\u7b2c\u4e8c\u9805\u7814\u7a76\u4e2d\uff0c\u5e38\u898f\u6cbb\u7642\u4e2d\u6dfb\u52a0Zytiga\u4e5f\u63d0\u9ad8\u4e86\u5b58\u6d3b\u7387\uff1a\u7d66\u85e5\u7d44\u4e09\u5e74\u5b58\u6d3b\u7387\u70ba83%\uff0c\u672a\u7d66\u85e5\u7d44\u70ba76%\u3002Zytiga\u9084\u6e1b\u5c11\u4e86\u5fa9\u767c\u6982\u7387\u548c\u56b4\u91cd\u9aa8\u9abc\u554f\u984c\u3002 \u91ab\u751f\u8aaa\uff0cZytiga\u9020\u6210\u5305\u62ec\u9ad8\u8840\u58d3\u5728\u5167\u7684\u66f4\u591a\u7684\u526f\u4f5c\u7528\uff0c\u4f46\u597d\u8655\u8d85\u904e\u4e86\u58de\u8655\u3002 \u4e3b\u8fa6\u9019\u6b21\u6703\u8b70\u7684\u8a72\u7d44\u7e54\u9996\u5e2d\u91ab\u7642\u5b98Richard Schilsky\u8aaa\uff0c\u9019\u4e9b\u7d50\u679c\u5c07\u300c\u5e7e\u4e4e\u4e00\u591c\u4e4b\u9593\u300d\u6539\u8b8a\u91ab\u7642\u505a\u6cd5\u3002\u4ed6\u8aaa\uff0c\u5927\u591a\u6578\u524d\u5217\u817a\u764c\u5df2\u64f4\u6563\u7537\u6027\u60a3\u8005\u5c07\u80fd\u5920\u4f7f\u7528Zytiga\u3002\u7f8e\u570b\u67092.5\u842c\u540d\u60a3\u8005\u548c\u5176\u4ed6\u570b\u5bb6\u66f4\u591a\u60a3\u8005\u88ab\u767c\u73fe\u8655\u65bc\u665a\u671f\u3002Zytiga\u5728\u7f8e\u570b\u7684\u8cbb\u7528\u70ba\u4e00\u500b\u6708\u7d041\u842c\u5143\u3002 \u80ba\u764c \u5728\u4e00\u9805\u5c0d303\u540d\u665a\u671f\u80ba\u764c\u60a3\u8005\u548c\u4e00\u7a2e\u88ab\u7a31\u4f5cALK\u7684\u57fa\u56e0\u7a81\u8b8a\u7684\u7814\u7a76\u4e2d\uff0cRoche\u7684Alecensa\u963b\u6b62\u764c\u75c7\u751f\u9577\u7684\u6642\u9593\u6bd4Pfizer\u7684Xalkori\u591a\u5341\u4e94\u500b\u6708\u3002\u5927\u7d045%\u80ba\u764c\u60a3\u8005\u2014\u2014\u7f8e\u570b\u6bcf\u5e74\u670912500\u540d\u80ba\u764c\u60a3\u8005\u2014\u2014\u5b58\u5728\u4e00\u7a2eALK\u7a81\u8b8a\uff0c\u9019\u7a2e\u7a81\u8b8a\u5728\u80ba\u764c\u5e74\u8f15\u4eba\u548c\u975e\u5438\u7159\u8005\u4e2d\u8868\u73fe\u5c24\u70ba\u660e\u986f\u3002 Alecensa\u963b\u6b62\u764c\u75c7\u60e1\u5316\u9577\u9054\u4e8c\u5341\u516d\u500b\u6708\uff0c\u800cXalkori\u50c5\u6709\u5341\u4e00\u500b\u6708\u3002\u5b83\u9084\u80fd\u66f4\u597d\u5730\u7a7f\u900f\u5927\u8166\uff1a\u5728\u63a5\u53d7\u6cbb\u7642\u7684\u7b2c\u4e00\u5e74\uff0c\u53ea\u67099%\u60a3\u8005\u7684\u80ba\u90e8\u816b\u7624\u64f4\u6563\u5230\u8166\u90e8\uff1b\u5728Xalkori\u60a3\u8005\u4e2d\uff0c\u9019\u4e00\u6bd4\u4f8b\u70ba41%\u3002Alecensa\u51fa\u73fe\u56b4\u91cd\u526f\u4f5c\u7528\u548c\u6b7b\u4ea1\u7684\u6982\u7387\u6e1b\u5c11\u3002 2015\u5e7412\u6708\uff0cFDA\u6279\u51c6\u9019\u7a2e\u85e5\u53ef\u7528\u65bc\u4f7f\u7528Xalkori\u5f8c\u4f9d\u7136\u60e1\u5316\u7684ALK\u76f8\u95dc\u80ba\u764c\u3002\u9019\u9805\u65b0\u7814\u7a76\u5c07\u5b83\u4f5c\u70ba\u521d\u59cb\u6cbb\u7642\u85e5\u7269\u9032\u884c\u6e2c\u8a66\uff0c\u76ee\u6a19\u662f\u8b93\u5b83\u7372\u5f97\u5168\u9762\u6279\u51c6\u3002 Xalkori\u6bcf\u500b\u6708\u8cbb\u7528\u5927\u7d04\u662f1\u842c\u5143\uff0cAlecensa\u70ba12500\u5143\u3002 \u4e73\u764c \u5728\u4e00\u9805\u907a\u50b3\u6027BRCA\u57fa\u56e0\u7a81\u8b8a\u5973\u6027\u91cd\u5927\u7814\u7a76\u4e2d\uff0c\u7b2c\u4e00\u6b21\uff0c\u4e00\u7a2e\u540d\u70baPARP\u6291\u5236\u5291\u7684\u65b0\u578b\u85e5\u7269\u5c55\u73fe\u5e0c\u671b\u3002\u907a\u50b3\u6027BRCA\u57fa\u56e0\u7a81\u8b8a\u52a0\u5287\u5973\u6027\u7f79\u60a3\u4e73\u764c\u98a8\u96aa\u3002PARP\u6291\u5236\u5291\u901a\u904e\u6291\u5236\u816b\u7624\u7d30\u80deDNA\u640d\u50b7\u4fee\u5fa9\u3001\u4fc3\u9032\u816b\u7624\u7d30\u80de\u767c\u751f\u51cb\u4ea1\u3002\u90e8\u5206PARP\u6291\u5236\u5291\u5df2\u7d93\u88ab\u6279\u51c6\u7528\u65bc\u6cbb\u7642\u5375\u5de2\u764c\u3002 \u8a72\u7814\u7a76\u5c0d302\u540d\u4e73\u764c\u5df2\u64f4\u6563\u5973\u6027\u60a3\u8005\u4f7f\u7528AstraZeneca\u7684Lynparza\u9032\u884c\u6e2c\u8a66\u3002Lynparza\u9069\u5ea6\u63a8\u9072\u4e86\u764c\u75c7\u60e1\u5316\u6642\u9593\u2014\u2014\u4e03\u500b\u6708\uff0c\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u4e09\u7a2e\u5e38\u7528\u5316\u7642\u65b9\u6cd5\u70ba\u56db\u500b\u6708\u3002Lynparza\u4e3b\u8981\u526f\u4f5c\u7528\u662f\u5641\u5fc3\u3001\u75b2\u52de\u548c\u8840\u6db2\u8a08\u6578\u554f\u984c\uff0c\u4f46\u51fa\u73fe\u56b4\u91cd\u554f\u984c\u7684\u6a5f\u6703\u6bd4\u5316\u7642\u8981\u5c11\u3002\u73fe\u5728\u9084\u4e0d\u77e5\u9053Lynparza\u662f\u5426\u80fd\u63d0\u9ad8\u751f\u5b58\u5e7e\u7387\u3002\u9019\u7a2e\u85e5\u6bcf\u500b\u6708\u5927\u7d04\u8981\u82b1\u8cbb13000\u5143\u3002 \u55ae\u4e00\u85e5\u7269? Loxo Oncology Inc.\u7684Larotrectinib\u91dd\u5c0d\u591a\u7a2e\u6709\u67d0\u4e00\u7279\u5b9a\u57fa\u56e0\u7570\u5e38\u7684\u6210\u4eba\u6216\u5152\u7ae5\u764c\u75c7\uff0c\u662f\u9019\u65b9\u9762\u7684\u9996\u7a2e\u65b0\u85e5\u3002\u57fa\u56e0\u554f\u984c\u5728\u4e0d\u52301%\u764c\u75c7\u4e2d\u767c\u751f\uff0c\u6240\u4ee5\u4e00\u500b\u5927\u554f\u984c\u662f\uff0c\u9664\u975e\u5ee3\u6cdb\u7684\u816b\u7624\u57fa\u56e0\u6aa2\u6e2c\u8b8a\u5f97\u6bd4\u73fe\u5728\u66f4\u52a0\u666e\u904d\uff0c\u5426\u5247\u9019\u4e9b\u7f55\u898b\u7684\u57fa\u56e0\u554f\u984c\u5982\u4f55\u88ab\u767c\u73fe\uff1f \u5728\u4e00\u9805\u5c0d\u670917\u7a2e\u4e0d\u540c\u764c\u75c750\u540d\u60a3\u8005\u6240\u9032\u884c\u7684\u7814\u7a76\u4e2d\uff0c76%\u5c0d\u9019\u7a2e\u85e5\u7269\u6709\u53cd\u61c9\uff0c\u4ed6\u5011\u7684\u75c5\u60c5\u6c92\u6709\u60e1\u5316\u3002\u9019\u7a2e\u85e5\u7269\u7684\u526f\u4f5c\u7528\u5305\u62ec\u75b2\u52de\u548c\u8f15\u5fae\u982d\u6688\u3002 \u8a72\u516c\u53f8\u5c07\u57fa\u65bc\u9019\u4e9b\u7d50\u679c\u5c0b\u6c42FDA\u6279\u51c6Larotrectinib\u3002\u4e0a\u500b\u6708\uff0cFDA\u8aaa\uff0c\u00a0Merck\u514d\u75ab\u6cbb\u7642\u85e5\u7269Ketruda\u53ef\u4ee5\u88ab\u7528\u65bc\u4efb\u4f55\u5e36\u6709\u7279\u5b9a\u57fa\u56e0\u7279\u5fb5\u7684\u5152\u7ae5\u6216\u6210\u4eba\u764c\u75c7\uff0c\u4f46Larotrectinib\u5c07\u662f\u6709\u53f2\u4ee5\u4f86\u7b2c\u4e00\u500b\u5728\u65e9\u671f\u958b\u767c\u968e\u6bb5\u5c31\u91dd\u5c0d\u7279\u5b9a\u57fa\u56e0\u7a81\u8b8a\u3001\u800c\u4e0d\u662f\u91dd\u5c0d\u7279\u5b9a\u764c\u7a2e\u7684\u65b0\u85e5\u3002","rel":"","context":"In &quot;\u5065\u5eb7\u990a\u751f&quot;","block_context":{"text":"\u5065\u5eb7\u990a\u751f","link":"https:\/\/newsforchinese.com\/v3\/category\/health\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2017\/06\/breastcancercells_600X378.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2017\/06\/breastcancercells_600X378.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2017\/06\/breastcancercells_600X378.jpg?resize=525%2C300&ssl=1 1.5x"},"classes":[]},{"id":150571,"url":"https:\/\/newsforchinese.com\/v3\/2018\/01\/14\/fda%e6%89%b9%e5%87%86brca%e7%aa%81%e8%ae%8a%e6%99%9a%e6%9c%9f%e4%b9%b3%e8%85%ba%e7%99%8c%e9%a6%96%e5%80%8b%e8%97%a5%e7%89%a9\/","url_meta":{"origin":120777,"position":1},"title":"FDA\u6279\u51c6BRCA\u7a81\u8b8a\u665a\u671f\u4e73\u817a\u764c\u9996\u500b\u85e5\u7269","author":"Raymond","date":"January 14, 2018","format":false,"excerpt":"\u9031\u4e94\uff0cFDA\u6279\u51c6\u6cbb\u7642BRCA\u7a81\u8b8a\u6240\u5f15\u8d77\u665a\u671f\u4e73\u817a\u764c\u7684\u9996\u500b\u85e5\u7269\u3002BRCA\u7a81\u8b8a\u662f\u9020\u6210\u7f79\u60a3\u60e1\u6027\u816b\u7624\u98a8\u96aa\u63d0\u9ad8\u7684\u907a\u50b3\u7f3a\u9677\u3002\u9019\u7a2e\u88ab\u7a31\u70balynparza\u7684\u85e5\u7269\u4e26\u4e0d\u662f\u65b0\u85e5\uff0c\u56e0\u70ba\u6578\u5e74\u524d\u5b83\u5df2\u7d93\u88ab\u6279\u51c6\u7528\u65bc\u5c0d\u5177\u6709\u76f8\u540c\u57fa\u56e0\u7a81\u8b8a\u665a\u671f\u5375\u5de2\u764c\u60a3\u8005\u7684\u6cbb\u7642\u3002FDA\u816b\u7624\u5b78\u5353\u8d8a\u4e2d\u5fc3\u4e3b\u4efbRichard Pazdur\u5728\u4e00\u4efd\u8072\u660e\u4e2d\u8aaa\uff0c\u64f4\u5927\u8a72\u85e5\u6838\u51c6\u9069\u7528\u65bc\u4e73\u817a\u764c\u60a3\u8005\u300c\u8b49\u660e\u76ee\u524d\u901a\u5e38\u8de8\u764c\u75c7\u985e\u578b\u958b\u767c\u4ee5\u816b\u7624\u6f5b\u5728\u907a\u50b3\u539f\u56e0\u70ba\u9776\u5411\u85e5\u7269\u7684\u7bc4\u5f0f\u3002\u300d Lynparza\u5c6c\u65bc\u540d\u70baPARP\u6291\u5236\u5291\u7684\u85e5\u7269\u7a2e\u985e\uff0cPARP\u6291\u5236\u5291\u5177\u5099\u963b\u65b7\u4e00\u7a2e\u53c3\u8207\u4fee\u5fa9\u53d7\u640dDNA\u7684\u9176\u7684\u4f5c\u7528\u3002FDA\u7a31\uff0c\u901a\u904e\u963b\u65b7\u9019\u7a2e\u9176\uff0c\u764c\u7d30\u80de\u5167DNA\u88ab\u4fee\u5fa9\u53ef\u80fd\u6027\u964d\u4f4e\uff0c\u5f9e\u800c\u5c0e\u81f4\u9019\u4e9b\u7d30\u80de\u6b7b\u4ea1\uff0c\u4e26\u9032\u800c\u53ef\u80fd\u6e1b\u7de9\u6216\u963b\u6b62\u816b\u7624\u751f\u9577\u3002 \u9019\u7a2e\u85e5\u7269\u4e5f\u88ab\u7a31\u70baolaparib\uff0c\u7531AstraZeneca\u548cMerck\u884c\u92b7\u3002 \u9031\u4e94\uff0cFDA\u9084\u6279\u51c6\u5c07Myriad Genetics\u540d\u70baBRACAnalysis CDx\u7684\u8a3a\u65b7\u6e2c\u8a66\u4f5c\u70baLynparza\u7684\u914d\u5957\u7522\u54c1\u3002\u9019\u9805\u6e2c\u8a66\u4ee5\u524d\u5df2\u88ab\u6279\u51c6\u7528\u65bc\u5375\u5de2\u764c\u60a3\u8005BRCA\u57fa\u56e0\u7a81\u8b8a\u6e2c\u8a66\uff0c\u73fe\u5728\u53c8\u53ef\u4ee5\u88ab\u7528\u65bc\u78ba\u5b9a\u54ea\u4e9b\u4e73\u817a\u764c\u60a3\u8005\u5b58\u5728BRCA\u57fa\u56e0\u7a81\u8b8a\u3002 National Cancer Institute\u4f30\u8a08\uff0c\u4eca\u5e74\u5927\u7d04\u6709253000\u540d\u5973\u6027\u5c07\u88ab\u8a3a\u65b7\u6709\u4e73\u817a\u764c\uff0c\u8d85\u904e40000\u540d\u5973\u6027\u5c07\u6b7b\u65bc\u4e73\u817a\u764c\u3002\u5927\u7d045%\u523010%\u4e73\u817a\u764c\u60a3\u8005\u5b58\u5728BRCA\u57fa\u56e0\u7a81\u8b8a\u3002","rel":"","context":"In &quot;\u5065\u5eb7\u990a\u751f&quot;","block_context":{"text":"\u5065\u5eb7\u990a\u751f","link":"https:\/\/newsforchinese.com\/v3\/category\/health\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2018\/01\/medcine.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2018\/01\/medcine.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2018\/01\/medcine.jpg?resize=525%2C300&ssl=1 1.5x"},"classes":[]},{"id":87053,"url":"https:\/\/newsforchinese.com\/v3\/2014\/09\/07\/%e9%bb%91%e8%89%b2%e7%b4%a0%e7%98%a4%e7%aa%81%e7%a0%b4%e6%80%a7%e6%96%b0%e8%97%a5keytruda%e7%8d%b2%e5%be%97fda%e6%89%b9%e5%87%86\/","url_meta":{"origin":120777,"position":2},"title":"\u9ed1\u8272\u7d20\u7624\u7a81\u7834\u6027\u65b0\u85e5Keytruda\u7372\u5f97FDA\u6279\u51c6","author":"Joce","date":"September 7, 2014","format":false,"excerpt":"\u9031\u56db\uff0cFDA\u6279\u51c6\u4e00\u7a2e\u65b0\u85e5\u3002\u9019\u7a2e\u85e5\u53ef\u80fd\u6539\u8b8a\u6700\u81f4\u547d\u76ae\u819a\u764c\u5f62\u5f0f\u9ed1\u8272\u7d20\u7624\u7684\u6cbb\u7642\u65b9\u5f0f\u3002 \u9019\u7a2e\u540d\u70baKeytruda\u85e5\u7684\u7814\u767c\u88ab\u8a8d\u70ba\u662f\u4e00\u6b21\u7a81\u7834\u3002\u5728\u7372\u5f97\u6279\u51c6\u4e4b\u524d\uff0c\u9019\u7a2e\u85e5\u5728\u8d85\u904e600\u4f4d\u9ed1\u8272\u7d20\u7624\u904d\u5e03\u5168\u8eab\u7684\u75c5\u4eba\u8eab\u4e0a\u9032\u884c\u4e86\u6e2c\u8a66\u3002\u6839\u64da\u7f8e\u570b\u764c\u75c7\u5b78\u6703\uff0c\u96d6\u7136\u9ed1\u8272\u7d20\u7624\u4f54\u76ae\u819a\u764c\u7e3d\u6578\u4e0d\u52302%\uff0c\u4f46\u5b83\u9020\u6210\u4e86\u5927\u591a\u6578\u76ae\u819a\u764c\u6b7b\u4ea1\u75c5\u4f8b\u3002 \u9ed1\u8272\u7d20\u7624\u7d30\u80de\u4f7f\u7528\u4e00\u7a2e\u540d\u70baPD-1\u7684\u7279\u5225\u86cb\u767d\u8cea\u4fdd\u8b77\u81ea\u8eab\u3002\u9019\u7a2e\u86cb\u767d\u8cea\u963b\u6b62\u514d\u75ab\u7cfb\u7d71\u8b58\u5225\u548c\u6bba\u6b7b\u764c\u75c7\u7d30\u80de\u3002 Keytruda\u662f\u4e00\u7a2e\u6297\u9ad4\uff0c\u4ee5\u9019\u7a2e\u86cb\u767d\u8cea\u70ba\u76ee\u6a19\u3002\u5982\u679c\u9ed1\u8272\u7d20\u7624\u7d30\u80de\u6c92\u6709\u9019\u7a2e\u86cb\u767d\u8cea\u7684\u9632\u8b77\uff0c\u90a3\u9ebc\u514d\u75ab\u7cfb\u7d71\u653b\u64ca\u764c\u75c7\u7d30\u80de\u7684\u6a5f\u6703\u5927\u589e\u3002 \u9019\u7a2e\u85e5\u4f7f\u7528\u8eab\u9ad4\u81ea\u8eab\u7684\u514d\u75ab\u7cfb\u7d71\uff0c\u9019\u610f\u5473\u8457\u8207\u5e38\u898f\u7684\u5316\u7642\u76f8\u6bd4\uff0c\u5b83\u7684\u526f\u4f5c\u7528\u53ef\u80fd\u66f4\u5c11\uff0c\u76ca\u8655\u66f4\u591a\u3002 \u5728\u63a5\u53d7\u9019\u7a2e\u85e5\u7269\u6e2c\u8a66\u7684\u75c5\u4eba\u4e2d\uff0c72%\u5c0d\u9019\u7a2e\u85e5\u7269\u6709\u53cd\u61c9\uff0c\u7d93\u66c6\u4e86\u816b\u7624\u7e2e\u5c0f\u7684\u73fe\u8c61\u3002\u8d85\u904e\u4e09\u5206\u4e4b\u4e00\u75c5\u4eba\u7684\u816b\u7624\u7e2e\u5c0f\u8d85\u904e\u4e09\u5206\u4e4b\u4e00\uff0c\u4e26\u4e14\u6c92\u6709\u91cd\u65b0\u751f\u9577\u3002 \u9019\u7a2e\u85e5\u7269\u6bcf\u4e09\u9031\u9032\u884c\u4e00\u6b21\u975c\u8108\u6ce8\u5c04\u3002\u76ee\u524d\u4e0d\u6e05\u695a\u75c5\u4eba\u7528\u85e5\u9700\u8981\u591a\u9577\u6642\u9593\u3002 \u7d71\u8a08\u6578\u64da\u986f\u793a\uff0c2014\u5e74\u7f8e\u570b\u5c07\u6709\u7d0476100\u500b\u65b0\u589e\u9ed1\u8272\u7d20\u7624\u75c5\u4f8b\uff0c\u4eca\u5e74\u6b7b\u65bc\u9019\u7a2e\u75be\u75c5\u7684\u4eba\u5c07\u90541\u842c\u4eba\u3002","rel":"","context":"In &quot;\u5065\u5eb7\u990a\u751f&quot;","block_context":{"text":"\u5065\u5eb7\u990a\u751f","link":"https:\/\/newsforchinese.com\/v3\/category\/health\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2014\/09\/keytruda.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2014\/09\/keytruda.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2014\/09\/keytruda.jpg?resize=525%2C300&ssl=1 1.5x"},"classes":[]},{"id":8544,"url":"https:\/\/newsforchinese.com\/v3\/2011\/01\/20\/breast-cancer-patients-worst-nightmare\/","url_meta":{"origin":120777,"position":3},"title":"\u4e73\u764c\u60a3\u8005\u6700\u9ed1\u6697\u7684\u5922\u9b58","author":"Raymond","date":"January 20, 2011","format":false,"excerpt":"\u6bcf\u5e74\uff0c4\u842c\u540d\u7f8e\u570b\u5a66\u5973\u6b7b\u4e8e\u4e73\u764c\u3002\u78ba\u5be6\uff0cAvastin\u4e0d\u80fd\u62ef\u6551\u5979\u5011\u7576\u4e2d\u7684\u591a\u6578\u4eba\u3002\u4f46\u662f\u5c0d\u65bc\u67d0\u4e00\u500b\u7fa4\u9ad4\uff0c\u9019\u500b\u85e5\u6709\u6548\u5ef6\u9577\u4e86\u751f\u547d\u3002\u5b83\u4e0d\u61c9\u8a72\u88ab\u653e\u5728\u6848\u677f\u4e0a\u3002","rel":"","context":"In &quot;\u5065\u5eb7\u990a\u751f&quot;","block_context":{"text":"\u5065\u5eb7\u990a\u751f","link":"https:\/\/newsforchinese.com\/v3\/category\/health\/"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":159058,"url":"https:\/\/newsforchinese.com\/v3\/2018\/07\/18\/stanford%e6%95%99%e6%8e%88%e9%96%8b%e7%99%bc%e7%a3%81%e5%8a%9b%e5%90%b8%e9%99%84%e7%99%8c%e7%b4%b0%e8%83%9e%e7%9a%84%e6%96%b9%e6%b3%95\/","url_meta":{"origin":120777,"position":4},"title":"Stanford\u6559\u6388\u958b\u767c\u78c1\u529b\u5438\u9644\u764c\u7d30\u80de\u7684\u65b9\u6cd5","author":"Yingying","date":"July 18, 2018","format":false,"excerpt":"Stanford University\u79d1\u5b78\u5bb6\u8aaa\uff0c\u4ed6\u5011\u5df2\u7d93\u958b\u767c\u51fa\u4e00\u7a2e\u78c1\u7dda\uff0c\u53ef\u4ee5\u7528\u300c\u5c07\u5bb6\u5ead\u7167\u7247\u5438\u9644\u5728\u51b0\u7bb1\u4e0a\u76f8\u540c\u7684\u529b\u300d\u5f9e\u8840\u6db2\u4e2d\u6293\u53d6\u816b\u7624\u7d30\u80de\u3002 \u78c1\u7dda\u88ab\u65cb\u5165\u975c\u8108\u4e2d\uff0c\u5438\u5f15\u53ef\u80fd\u5728\u8840\u6db2\u4e2d\u6d41\u52d5\u7684\u816b\u7624\u7d30\u80de\u3002\u7814\u7a76\u4eba\u54e1\u8aaa\uff0c\u9019\u7a2e\u6280\u8853\u6bd4\u76ee\u524d\u7684\u764c\u75c7\u6aa2\u6e2c\u65b9\u6cd5\u591a\u5438\u5f1510\u523080\u500b\u816b\u7624\u7d30\u80de\uff0c\u9019\u610f\u5473\u8457\u78c1\u7dda\u53ef\u4ee5\u5e6b\u52a9\u63d0\u524d\u9396\u5b9a\u764c\u75c7\u3002 Stanford\u653e\u5c04\u5b78\u4e3b\u4efb\u548cStanford\u764c\u75c7\u65e9\u671f\u6aa2\u6e2cCanary\u4e2d\u5fc3\u4e3b\u4efb\u3001\u7814\u7a76\u9818\u5c0e\u8005Sanjiv Gambhir\u8aaa\uff0c\u78c1\u529b\u6548\u7528\u9060\u4e0d\u6b62\u53ea\u7528\u65bc\u764c\u75c7\u6aa2\u6e2c\u3002 \u300c\u5b83\u53ef\u80fd\u5c0d\u4efb\u4f55\u8840\u6db2\u4e2d\u6709\u76f8\u95dc\u7d30\u80de\u6216\u5206\u5b50\u7684\u5176\u4ed6\u75be\u75c5\u6709\u7528\uff0c\u300d\u4ed6\u88dc\u5145\u8aaa\uff0c\u5305\u62ec\u7d30\u83cc\u611f\u67d3\u548c\u708e\u75c7\u5f15\u8d77\u7684\u75c5\u75c7\u3002 Gambhir\u548c\u4ed6\u7684\u5408\u8457\u8005\u9031\u4e00\u5728Nature Biomedical Engineering\u4e0a\u767c\u8868\u4e86\u7814\u7a76\u7d50\u679c\u3002 \u5728\u8840\u6db2\u4e2d\u8ff4\u5708\u7684\u816b\u7624\u7d30\u80de\u662f\u764c\u75c7\u751f\u7269\u6a19\u8a8c\u7269\uff0c\u4f46\u9019\u4e9b\u7d30\u80de\u5f80\u5f80\u662f\u7a00\u7f3a\u7684\uff0c\u56e0\u6b64\u901a\u904e\u62bd\u8840\u6aa2\u6e2c\u5b83\u5011\u7684\u96e3\u5ea6\u662f\u76f8\u7576\u5927\u3002 \u64daGambhir\uff0c\u5728\u9032\u884c\u5e38\u898f\u8840\u6db2\u6aa2\u67e5\u5f8c\uff0c\u91ab\u751f\u5f88\u5bb9\u6613\u5f97\u51fa\u7d50\u8ad6\uff1a\u300c\u4ec0\u9ebc\u90fd\u6c92\u6709\u300d\u3002 \u78c1\u7dda\u539a\u5ea6\u7b49\u65bc\u8ff4\u7d0b\u91dd\uff0c\u9577\u5ea6\u76f8\u7576\u65bc\u5c0f\u6307\u3002\u5b83\u901a\u904e\u652b\u53d6\u7d0d\u7c73\u9846\u7c92\u78c1\u5316\u816b\u7624\u7d30\u80de\u767c\u63ee\u4f5c\u7528\u3002\u7576\u5e36\u96fb\u7d30\u80de\u901a\u904e\u5b83\u6642\uff0c\u5b83\u5c0d\u5b83\u5011\u7522\u751f\u5438\u9644\u3002\u6b64\u5f8c\uff0c\u76f8\u95dc\u4eba\u54e1\u53ef\u4ee5\u5c07\u5b83\u5f9e\u8840\u6d41\u4e2d\u53d6\u51fa\u9032\u884c\u5206\u6790\u3002 Gambhir\u8aaa\uff1a\u300c\u6211\u5011\u4f30\u8a08\u5927\u7d04\u9700\u898180\u7ba1\u8840\u6db2\u624d\u80fd\u5339\u914d\u78c1\u7dda\u572820\u5206\u9418\u5167\u6240\u53d6\u7684\u6a23\u54c1\u3002\u300d \u79d1\u5b78\u5bb6\u5011\u50c5\u5728\u8c6c\u8eab\u4e0a\u6e2c\u8a66\u4e86\u9019\u9805\u6280\u8853\uff0c\u76ee\u524d\u6b63\u7b49\u5f85FDA\u6279\u51c6\u9032\u884c\u4eba\u9ad4\u8a66\u9a57\u3002 \u6b64\u5916\uff0c\u78c1\u7dda\u5176\u4ed6\u7528\u9014\u4e5f\u53ef\u80fd\u88ab\u6e2c\u8a66\uff0c\u5305\u62ec\u6cbb\u7642\u764c\u75c7\u6216\u9632\u6b62\u764c\u75c7\u64f4\u6563\u3002 \u300c\u5982\u679c\u6211\u5011\u80fd\u8b93\u9019\u4ef6\u6771\u897f\u771f\u6b63\u5730\u5438\u9644\u764c\u7d30\u80de\uff0c\u4f60\u53ef\u4ee5\u8003\u616e\u4e00\u7a2e\u61c9\u7528\uff1a\u8b93\u4f60\u5728\u66f4\u9577\u6642\u9593\u5167\u9060\u96e2\u764c\u7d30\u80de\u3002\u300dGambhir\u8aaa\u3002\u300c\u9019\u6a23\uff0c\u5b83\u5e7e\u4e4e\u5c31\u50cf\u4e00\u500b\u7be9\u6aa2\u7a0b\u5f0f\uff0c\u6293\u4f4f\u764c\u7d30\u80de\uff0c\u9632\u6b62\u5b83\u5011\u64f4\u6563\u5230\u8eab\u9ad4\u7684\u5176\u4ed6\u90e8\u4f4d\u3002\u300d","rel":"","context":"In &quot;Technology&quot;","block_context":{"text":"Technology","link":"https:\/\/newsforchinese.com\/v3\/category\/technology\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2018\/07\/lab.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2018\/07\/lab.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2018\/07\/lab.jpg?resize=525%2C300&ssl=1 1.5x"},"classes":[]},{"id":68580,"url":"https:\/\/newsforchinese.com\/v3\/2014\/02\/12\/sunnyvale%e7%9a%84pharmacyclics%e7%99%bd%e8%a1%80%e7%97%85%e8%97%a5%e7%89%a9%e7%8d%b2\/","url_meta":{"origin":120777,"position":5},"title":"Sunnyvale\u7684Pharmacyclics\u767d\u8840\u75c5\u85e5\u7269\u7372","author":"Joce","date":"February 12, 2014","format":false,"excerpt":"FDA\u661f\u671f\u4e09\u6279\u51c6Pharmacyclics\u548cJohnson\u00a0&\u00a0Johnson\u7814\u767c\u7684\u4e00\u7a2e\u6cbb\u7642\u7f55\u898b\u8840\u6db2\u548c\u9aa8\u9ad3\u75be\u75c5\u7684\u6297\u764c\u85e5\u7269\u3002FDA\u7a31\u6279\u51c6\u81f3\u5c11\u63a5\u53d7\u904e\u4e00\u6b21\u5176\u4ed6\u65b9\u6cd5\u6cbb\u7642\u7684\u75c5\u4eba\u4f7f\u7528Imbruvica\u3002\u9019\u7a2e\u85e5\u7269\u6240\u91dd\u5c0d\u7684\u75be\u75c5\u5f15\u767c\u767d\u8840\u7d30\u80de\u5806\u7a4d\uff0c\u4e26\u9010\u6f38\u5f9e\u9aa8\u9ad3\u64f4\u6563\u5230\u6dcb\u5df4\u7d50\u4ee5\u53ca\u5176\u4ed6\u5668\u5b98\u3002National\u00a0Cancer\u00a0Institute\u4f30\u8a082013\u5e74\u7f8e\u570b\u670915,680\u4eba\u88ab\u8a3a\u65b7\u60a3\u6709\u9019\u7a2e\u7f55\u898b\u764c\u75c7\uff0c4,580\u4eba\u6b7b\u65bc\u9019\u7a2e\u75be\u75c5\u3002 \u661f\u671f\u4e09\u662fImbruvica\u7b2c\u4e8c\u6b21\u7372\u5f97\u6279\u51c6\uff0cFDA\u65bc\u53bb\u5e7411\u6708\u6279\u51c6\u5176\u7528\u65bc\u5957\u7ec6\u80de\u6dcb\u5df4\u7624(MCL)\uff0c \u9019\u7a2e\u85e5\u7269\u901a\u904e\u963b\u65b7\u5e6b\u52a9\u764c\u75c7\u8907\u88fd\u548c\u64f4\u6563\u7684\u86cb\u767d\u8cea\u4f86\u767c\u63ee\u6cbb\u7642\u4f5c\u7528\u3002\u57fa\u65bc\u5c0d\u5df2\u63a5\u53d7\u904e\u5176\u4ed6\u65b9\u6cd5\u6cbb\u764248\u4f4d\u75c5\u4eba\u7684\u7814\u7a76\uff0c\u76e3\u7ba1\u6a5f\u69cb\u6279\u51c6\u4e86\u9019\u4e00\u85e5\u7269\u7684\u65b0\u7528\u9014\u3002\u7d50\u679c\u986f\u793a58%\u75c5\u4eba\u7684\u816b\u7624\u5728\u4f7f\u7528Imbruvica\u5f8c\u7e2e\u5c0f\u3002\u9019\u4e00\u85e5\u7269\u7684\u7814\u7a76\u4ecd\u5728\u9032\u884c\u4e2d\uff0c\u5c0d\u5ef6\u9577\u751f\u547d\u662f\u5426\u6709\u63d0\u9ad8\u4f5c\u7528\u5c1a\u672a\u78ba\u5b9a\u3002 Imbruvica\u7531\u7e3d\u90e8\u5728Sunnyvale\u7684Pharmacyclics\u751f\u7522\uff0c\u7531\u5f37\u751f\u516c\u53f8New\u00a0Brunswick\u5206\u90e8Janssen\u00a0Biotech\u884c\u92b7\u3002 Pharmacyclics\u80a1\u7968\u661f\u671f\u4e09\u4ea4\u6613\u4e2d\u4e0a\u6f32$4.15\u5230$137\uff0c\u4e0a\u6f32\u5e45\u5ea6\u70ba3.1%\uff0c\u5f37\u751f\u80a1\u7968\u5fae\u8dcc55\u5206\u5230$92.42\u3002","rel":"","context":"In &quot;\u5065\u5eb7\u990a\u751f&quot;","block_context":{"text":"\u5065\u5eb7\u990a\u751f","link":"https:\/\/newsforchinese.com\/v3\/category\/health\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2014\/02\/imbru.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2014\/02\/imbru.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2014\/02\/imbru.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/newsforchinese.com\/v3\/wp-content\/uploads\/2014\/02\/imbru.jpg?resize=700%2C400&ssl=1 2x"},"classes":[]}],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/newsforchinese.com\/v3\/wp-json\/wp\/v2\/posts\/120777","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newsforchinese.com\/v3\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsforchinese.com\/v3\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsforchinese.com\/v3\/wp-json\/wp\/v2\/users\/1001012"}],"replies":[{"embeddable":true,"href":"https:\/\/newsforchinese.com\/v3\/wp-json\/wp\/v2\/comments?post=120777"}],"version-history":[{"count":0,"href":"https:\/\/newsforchinese.com\/v3\/wp-json\/wp\/v2\/posts\/120777\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsforchinese.com\/v3\/wp-json\/wp\/v2\/media\/120778"}],"wp:attachment":[{"href":"https:\/\/newsforchinese.com\/v3\/wp-json\/wp\/v2\/media?parent=120777"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsforchinese.com\/v3\/wp-json\/wp\/v2\/categories?post=120777"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsforchinese.com\/v3\/wp-json\/wp\/v2\/tags?post=120777"},{"taxonomy":"series","embeddable":true,"href":"https:\/\/newsforchinese.com\/v3\/wp-json\/wp\/v2\/series?post=120777"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}